Diuretics: 1, 2, 4-Benzothiadiazine-1, 1-dioxides

FC NOVELLO, SC BELL, ELA ABRAMS…

Index: Novello,F.C. et al. Journal of Organic Chemistry, 1960 , vol. 25, p. 970 - 981

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Citation Number: 60

Abstract

Grana and L. Lilla, Ed. Sci., 12, 65 (1957). amide by reaction with acylating agents, aldehydes or urea. However, no compound of this class has been reported where a sulfamyl group is present. The only biologic property previously noted for any 1, 2, 4- benzothiadiazine-l, l-dioxide is the sweet taste of 3-oxodihydro-1, 2, 4-benzothiadiazine-l, l- di~ xide.~~~~~ In our studies, compounds of greatest interest have the general structures ...