Tetrahedron

Synthesis of aromatic aldehydes by organocatalytic [4+ 2] and [3+ 3] cycloaddition of α, β-unsaturated aldehydes

BC Hong, HC Tseng, SH Chen

Index: Hong, Bor-Cherng; Tseng, Hsing-Chang; Chen, Shang-Hung Tetrahedron, 2007 , vol. 63, # 13 p. 2840 - 2850

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Citation Number: 63

Abstract

Organocatalytic inter-and intramolecular [4+ 2] and [3+ 3] cycloadditions of α, β-unsaturated aldehydes to give polysubstituted aromatic aldehydes are described. High periselectivity for the cycloadditions, with catalyst effects exerted by l-proline and pyrrolidine–HOAc, as well as cocatalyst, additive effects, has been observed.

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