An Interesting Benzyne-Mediated Annulation Leading to Benzo [a] pyrene

A Cobas, E Guitián, L Castedo

Index: Cobas, Agustin; Guitian, Enrique; Castedo Journal of Organic Chemistry, 1997 , vol. 62, # 15 p. 4896 - 4897

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Citation Number: 24

Abstract

The Diels-Alder reactionsone of the most useful synthetic transformations in organic synthesisshas been the subject of a huge amount of theoretical and experimental work in the last 10 years. In spite of this, the closely related cycloaddition reaction between a conjugated enyne and a dienophile, known as the dehydro Diels-Alder reaction (DDAR), remains relatively unknown. 1 Scheme 1 shows a general representation of this reaction ( ...