Tetrahedron Letters

Complex base-induced generation of 3, 4-dehydroquinoline: a new access to quinoline derivatives

S Blanchard, G Guillaumet, P Caubère

Index: Blanchard, Stephanie; Guillaumet, Gerald; Caubere, Paul Tetrahedron Letters, 2001 , vol. 42, # 40 p. 7037 - 7039

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Citation Number: 7

Abstract

As part of a program of medicinal chemistry undertaken a few years ago, 1., , , , and we are pursuing investigations on the synthesis and reactivity of heterocycles containing nitrogen. Recently we were confronted with the preparation of quinoline derivatives. Our experience in arynic chemistry , and 2. led us to consider the use of didehydroquinolines as intermediates. Taking account of the results previously obtained in the pyridine series, 2., and we anticipated that these ...