Reductive Amination of Aldehydes and Amines with an Efficient Pd/NiO Catalyst

H Yang, X Cui, Y Deng, F Shi

Index: Yang, Huimin; Cui, Xinjiang; Deng, Youquan; Shi, Feng Synthetic Communications, 2014 , vol. 44, # 9 p. 1314 - 1322

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Abstract

The formation of N-alkyl amines is one of the most important transformations in organic chemistry. [ 1–2 View all references ] In particular, N-alkyl amines are important building blocks for natural products, pharmaceuticals, and agrochemicals. The reaction of amines and alkyl halides with the addition of stoichiometric amounts of inorganic bases is the most effective and universal method. [ 3–5 View all references ] However, this method often suffers from drawbacks ...