Stereoselective catalytic Tishchenko reduction of β-hydroxyketones using scandium triflate
KM Gillespie, IJ Munslow, P Scott
Index: Gillespie, Kevin M.; Munslow, Ian J.; Scott, Peter Tetrahedron Letters, 1999 , vol. 40, # 52 p. 9371 - 9374
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Citation Number: 32
Abstract
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A number of aliphatic and aromatic β-hydroxyketones were reduced to 1,3-diol monoesters by aldehydes in the presence of a catalytic amount of scandium triflate. Chiral substrates were reduced with high 1,3-anti diastereoselectivity. ... Sc(OTf) 3 catalyses the highly diastereoselective ...
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