Palladium-Catalyzed Bond Reorganization of 1, 3-Diynes: An Entry to Diverse Functionalized 1, 5-Dien-3-ynes

W Wu, Y Gao, H Jiang, Y Huang

Index: Wu, Wanqing; Gao, Yang; Jiang, Huanfeng; Huang, Yubing Journal of Organic Chemistry, 2013 , vol. 78, # 9 p. 4580 - 4586

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Citation Number: 7

Abstract

A mild and efficient method for the synthesis of functionalized 1, 5-dien-3-ynes from 1, 3- diynes under PdII catalysis is described. The process allows quick and atom-economical assembly of various dihalo-, haloacyl-, and diacyl-substituted 1, 5-dien-3-ynes in high yields. The switch of selectivity in the formation of these dienyne products can be controlled by the choice of catalysis system and reaction conditions.