Primary tert??and sec??Allylamines via Palladium??Catalyzed Hydroamination and Allylic Substitution with Hydrazine and Hydroxylamine Derivatives

AM Johns, Z Liu, JF Hartwig

Index: Johns, Adam M.; Liu, Zhijian; Hartwig, John F. Angewandte Chemie - International Edition, 2007 , vol. 46, # 38 p. 7259 - 7261

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Citation Number: 73

Abstract

The challenge of controlling the regiochemistry of palladiumcatalyzed allylic substitution by choice of ancillary ligand has a long history. Much attention has been focused on controlling regiochemistry because formation of the more substituted product could be developed into a mild route to sec-and even tert-alkylamines (Scheme 1). kermark and co-workers reported that attack can occur at the more substituted position of a prenyl complex, but that the ...