(R)-and (S)-cyanohydrins using oxynitrilases in whole cells
E Kiljunen, LT Kanerva
Index: Kiljunen, Eero; Kanerva, Liisa T. Tetrahedron Asymmetry, 1996 , vol. 7, # 4 p. 1105 - 1116
Full Text: HTML
Citation Number: 65
Abstract
Almond meal and Sorghum bicolor shoots were used as the sources of oxynitrilases for the preparation of a number (R)-and (S)-arylcyanohydrins, respectively, from the corresponding aldehydes in diisopropyl ether. Two different in situ methods were used to introduce hydrogen cyanide into the reaction mixture. In method 1, acetone cyanohydrin decomposes enzymatically and/or chemically to hydrogen cyanide. In method 2, hydrogen cyanide ...
Related Articles:
[Casas, Jesus; Najera, Carmen; Sansano, Jose M.; Saa, Jose M. Organic Letters, 2002 , vol. 4, # 15 p. 2589 - 2592]
A new (R)-hydroxynitrile lyase from Prunus mume: asymmetric synthesis of cyanohydrins
[Nanda, Samik; Kato, Yasuo; Asano, Yasuhisa Tetrahedron, 2005 , vol. 61, # 46 p. 10908 - 10916]
Asymmetric cyanohydrin formation from aldehydes catalyzed by manganese Schiff base complexes
[Qu, Yanyang; Jing, Linhai; Wu, Zhiqing; Wu, Di; Zhou, Xiangge Tetrahedron Asymmetry, 2010 , vol. 21, # 2 p. 187 - 190]
Synthesis of optically active silyl protected cyanohydrins
[Tetrahedron, , vol. 46, # 3 p. 979 - 986]
Kinetic resolution of cyanohydrins via enantioselective acylation catalyzed by lipase PS-30
[Tetrahedron Letters, , vol. 49, # 45 p. 6440 - 6441]