Tetrahedron

A novel NH 4 OAc and CuBr (PPh 3) 3-induced intermolecular Pummerer-type reaction between free (NH)-indoles and dimethylsulfoxide: facile synthesis of 3- …

J Liu, X Wang, H Guo, X Shi, X Ren, G Huang

Index: Liu, Jin; Wang, Xianxue; Guo, Han; Shi, Xiaokang; Ren, Xiaoyu; Huang, Guosheng Tetrahedron, 2012 , vol. 68, # 5 p. 1560 - 1565

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Citation Number: 8

Abstract

3-Alkyl substituted indoles have potentially high biological activities. 1 They have also been used to synthesis complex indole derivatives that can be used as pharmaceuticals and agrochemicals. 2 Among all the 3-alkyl substituted indoles, 3-methylthiomethyl substituted indoles have attracted most interest because they are naturally presented in some indole alkaloids and they show excellent anti-insect activity. 3 For instance, dithyreanitrile, which had been ...