Highly Branched Alkylphosphorus Compounds. I. Synthesis of 2, 3-Dimethylbutylphosphonyl Chloride1, 2
SH Metzger, AF Isbell
Index: Metzger,S.H.; Isbell,A.F. Journal of Organic Chemistry, 1964 , vol. 29, p. 623 - 627
Full Text: HTML
Citation Number: 5
Abstract
Although this rigorous synthesis presented a number of problems, all were solved. Alkylation of malonic ester (111) with methyl iodide produced IV, which was separated from unalkylated I11 by the excellent procedure of; 11ichaeL8 Following the procedure of Wallingford, Thorpe, and Homeyer,'IV was alkylated with isopropyl bromide, giving V. The acid (VI) and the alcohol (VII) were produced by relatively conventional procedures as ...
Related Articles:
Mechanism for inversion in primary organomagnesium compounds
[Fraenkel,G. et al. Journal of the American Chemical Society, 1971 , vol. 93, p. 1704 - 1708]
Reactions of a graded set of radicals with N-bromosuccinimide; two transition states
[Tlumak, Robert L.; Skell Philip S. Journal of the American Chemical Society, 1982 , vol. 104, # 25 p. 7267 - 7274]
Reactions of BrCl with alkyl radicals.
[Skell, P. S.; Baxter, H. N.; Tanko, J. M. Tetrahedron Letters, 1986 , vol. 27, # 43 p. 5181 - 5184]
Synthesis of campesteryl acetate ((24R)-24-methyl-3β-acetoxycholesten-5-ene) and its 24S-epimer
[Ikan,R. et al. Steroids, 1970 , vol. 16, p. 517 - 522]