Advanced Synthesis & Catalysis

Functionalizations of Aryl C H Bonds in 2??Arylpyridines via Sequential Borylation and Copper Catalysis

L Niu, H Yang, D Yang, H Fu

Index: Niu, Liting; Yang, Haijun; Yang, Daoshan; Fu, Hua Advanced Synthesis and Catalysis, 2012 , vol. 354, # 11-12 p. 2211 - 2217

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Citation Number: 28

Abstract

Abstract Selective functionalizations of aryl C [BOND] H bonds in 2-arylpyridines have been developed via sequential borylation and aerobic oxidative copper catalysis, and the corresponding aryl halides, sulfones, azides and arylamines were obtained in good yields. The protocol uses cheap and readily available boron tribromide (BBr 3) as the borylating reagent, and inorganic salts (potassium iodide, ammonium bromide, sodium ...

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