Pd (II)-Catalyzed Carbonylation of C (sp3)− H Bonds: A New Entry to 1, 4-Dicarbonyl Compounds

EJ Yoo, M Wasa, JQ Yu

Index: Giri, Ramesh; Lam, Jonathan K.; Yu, Jin-Quan Journal of the American Chemical Society, 2010 , vol. 132, # 2 p. 686 - 693

Full Text: HTML

Citation Number: 163

Abstract

Pd (II)-catalyzed β-C (sp3)− H carbonylation of N-arylamides under CO (1 atm) has been achieved. Following amide-directed C (sp3)− H cleavage and insertion of CO into the resulting [Pd (II)− C (sp3)] bond, intramolecular C− N reductive elimination gave the corresponding succinimides, which could be readily converted to 1, 4-dicarbonyl compounds. This method was found to be effective with substrates containing α-hydrogen ...

Related Articles:

The synthesis and resolution of 2, 2'-, 4, 4'-, and 6, 6'-substituted chiral biphenyl derivatives for application in the preparation of chiral materials

[Montoya-Pelaez, Pedro J.; Uh, Yoon-Seo; Lata, Christopher; Thompson, Matthew P.; Lemieux, Robert P.; Crudden, Cathleen M. Journal of Organic Chemistry, 2006 , vol. 71, # 16 p. 5921 - 5929]

The synthesis and resolution of 2, 2'-, 4, 4'-, and 6, 6'-substituted chiral biphenyl derivatives for application in the preparation of chiral materials

[Montoya-Pelaez, Pedro J.; Uh, Yoon-Seo; Lata, Christopher; Thompson, Matthew P.; Lemieux, Robert P.; Crudden, Cathleen M. Journal of Organic Chemistry, 2006 , vol. 71, # 16 p. 5921 - 5929]

More Articles...