Heterocycles of biological importance. Part 1. Novel synthesis and biological activity study of 5??Alkyl and 5??Aryl??7??aminopyrazolo [1, 5??a]??pyrimidines from allenic or …

ZT Fomum, PF Asobo…

Index: Fomum; Asobo; Ifeadike Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1125 - 1128

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Citation Number: 3

Abstract

Abstract Allenic nitriles react with 3-aminopyrazole in ethanol or dimethylformamide to give 5- alkyl-7-aminopyrazolo [1, 5-a] pyrimidines 5 of pharmaceutical interest in good yields. 3- Phenylpropynenitrile reacts with 3-aminopyrazole in a similar manner to give the aryl