Tetrahedron letters

A vicarious aromatic substitution approach to aklavinone from chrysazin

RA Murphy, MP Cava

Index: Murphy, Raymond A.; Cava, Michael P. Tetrahedron Letters, 1984 , vol. 25, # 8 p. 803 - 806

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Citation Number: 23

Abstract

Abstract The cheap, available dye-intermediate 1, 8-dihydroxyanthraquinone (2) is converted efficiently to a useful aklavinone precursor (3). A Mitsunobu alkylation-Claisen rearrangement sequence and an unprecedented vicarious aromatic substitution on an anthraquinone are employed as key steps.

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