Tetrahedron letters

Reusable resin plug-bound palladium catalysts for organic synthesis

B Atrash, J Reader, M Bradley

Index: Atrash, Butrus; Reader, John; Bradley, Mark Tetrahedron Letters, 2003 , vol. 44, # 25 p. 4779 - 4782

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Citation Number: 31

Abstract

Resin plugs, a unique and conveniently handled form of resin, prepared by sintering high- density polyethylene (HDPE) with pre-functionalised resins, were derivatised and loaded with palladium (0). These 'plugs' were used in the preparation of a Suzuki reaction based library and the removal of allyl ester protecting groups. The 'plugs of catalyst'were easily separated from the reaction mixture and were re-used multiple times with minimal loss of ...

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