Tetrahedron Letters

Synthesis of tetracyclic pyrrolidine/isoxazolidine fused pyrano [3, 2-h] quinolines via intramolecular 1, 3-dipolar cycloaddition in ionic liquid

A Hazra, YP Bharitkar, A Maity, S Mondal, NB Mondal

Index: Hazra, Abhijit; Bharitkar, Yogesh P.; Maity, Arindam; Mondal, Shyamal; Mondal, Nirup B. Tetrahedron Letters, 2013 , vol. 54, # 32 p. 4339 - 4342

Full Text: HTML

Citation Number: 4

Abstract

Tetracyclic pyrrolidine/isoxazolidine fused pyrano [3, 2-h] quinolines were synthesized via intramolecular 1, 3-dipolar cycloaddition in ionic liquid. The transformations are operationally simple and environment-friendly in nature. The reaction is highly stereoselective affording exclusively the cis fused products, as deduced by the small coupling constant value (J= 4.8 Hz) between ring juncture protons which also showed ...