Tetrahedron

A novel approach to 4-benzylisoouinolines

U Berger, T Burgemeister, G Dannhardt, KK Mayer…

Index: Berger, U.; Burgemeister, Th.; Dannhardt, G.; Mayer, K. K.; Wiegrebe, W. Tetrahedron, 1984 , vol. 40, # 1 p. 215 - 220

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Citation Number: 4

Abstract

The reaction of quinone methides with 3.4-dihydroisoquinoline or isoquinoline leads to benzylisoquinoline derivatives. NMR and ms investigations as well as chemical degradation prove that benzylation takes place at C-4 of the isoquinoline nucleus. Spectroscopic data are given for all new compounds.