Expedient synthesis of α-substituted fluoroethenes

SK Mandal, AK Ghosh, R Kumar, B Zajc

Index: Mandal, Samir K.; Ghosh, Arun K.; Kumar, Rakesh; Zajc, Barbara Organic and Biomolecular Chemistry, 2012 , vol. 10, # 16 p. 3164 - 3167

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Citation Number: 16

Abstract

A mild and efficient synthesis of 1-aryl-1-fluoroethenes from benzothiazolyl (aryl) fluoromethyl sulfones and paraformaldehyde, under DBU-or Cs2CO3-mediated conditions at room temperature, is described. A comparable diethyl fluoro (naphthalen-2-yl) methylphosphonate reagent does not react with paraformaldehyde under these mild conditions. The utility of the methodology for synthesis of terminal α-fluoroalkenes bearing ...