Phosphorus and Sulfur and the Related Elements

New perspectives in thiazole chemistry

A Dondoni

Index: Dondoni, Alessandro Phosphorus and Sulfur and the Related Elements, 1985 , vol. 24, p. 1 - 38

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Citation Number: 14

Abstract

Abstract Carbon-carbon bond forming reactions at C-2 of the thiazole ring have been carried using two strategies, one involving the addition of organometallic reagents (lithium carbanions of esters, Grignard salts, silyl enol ethers, silyl ketene acetals, silylazoles) to N- acylthiazolium salts; the other involving the addition of carbon electrophiles (ketenes, acyl chlorides, anhydrides, aldehydes) to N-acylthiazolium ylides generated in situ. The ...

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