Glycerol/hypophosphorous acid: An efficient system solvent-reducing agent for the synthesis of 2-organylselanyl pyridines
S Thurow, R Webber, G Perin, EJ Lenardão, D Alves
Index: Thurow, Samuel; Webber, Rodrigo; Perin, Gelson; Lenardao, Eder J.; Alves, Diego Tetrahedron Letters, 2013 , vol. 54, # 24 p. 3215 - 3218
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Citation Number: 26
Abstract
We describe herein an efficient and simple method to synthesize 2-organylselanyl pyridines by reactions of 2-chloropyridines with organylselenols, generated in situ by reaction of diorganyl diselenides, using glycerol as solvent and hypophosphorous acid (H3PO2) as reducing agent. Using this methodology, a range of selenium substituted pyridines was obtained in high yields. The system solvent-reducing agent glycerol/H3PO2 can be easily ...
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