Tetrahedron letters

α′-Silylated tertiary benzamides as dual ortho-and α′-carbanion synthons. Carbodesilylative routes to isoquinoline and dibenzoquinolizidine derivatives

JC Cuevas, V Snieckus

Index: Cuevas, J.-C.; Snieckus, V. Tetrahedron Letters, 1989 , vol. 30, # 43 p. 5837 - 5840

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Citation Number: 27

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Compounds 5a-h were prepared by treatment of the appropriate secondary amide with chloromethyltrimethyl silane under NaH/DMF/RT conditions. ... Other electrophiles can also be incorporated, eg 6, R 1 = H, E = D(MeOD) (92%) and Me (MeI) (94%). ... This reaction was first achieved by ...

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