Tetrahedron Letters

One-pot esterification-click (CuAAC) and esterification–acetylene coupling (Glaser/Eglinton) for functionalization of Wang polystyrene resin

S Eppel, M Portnoy

Index: Eppel, Sagi; Portnoy, Moshe Tetrahedron Letters, 2013 , vol. 54, # 37 p. 5056 - 5060

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Citation Number: 5

Abstract

Abstract We report three new sets of one-pot reactions for functionalization of Wang polystyrene resin and its derivatives. We first show that it is possible to combine esterification and CuAAC (Copper-Catalyzed Alkyne-Azide Cycloaddition) in a one-pot reaction with a very high yield. We also demonstrate for the first time that it is possible to combine esterification with either Glaser or Eglinton acetylene-couplings in a one-pot reaction. ...