An efficient one??pot procedure for the preparation of 1, 3, 4??thiadiazoles in ionic liquid [bmim] BF4 as dual solvent and catalyst

S Rostamizadeh, R Aryan, HR Ghaieni…

Index: Rostamizadeh, Shahnaz; Aryan, Reza; Ghaieni, Hamid R.; Amani, Ali M. Heteroatom Chemistry, 2008 , vol. 19, # 3 p. 320 - 324

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Citation Number: 7

Abstract

Abstract The one-pot three component condensation of hydrazine hydrate with substituted phenylisothiocyanates followed by the addition of substituted benzaldehydes in the presence of ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim] BF 4) and in the absence of any other catalyst under mild condition afforded 1, 3, 4-thiadiazoles in excellent yields. The reaction workup is simple, and the ionic liquid was easily recovered ...