Il Farmaco

Synthesis and antimicrobial activity of new 7β-(benzo [a] dihydrocarbazolyloxyacetyl)-substituted cephalosporins

…, S Rapposelli, M Macchia, E Di Modugno, A Balsamo

Index: Rossello, Armando; Orlandini, Elisabetta; Nuti, Elisa; Rapposelli, Simona; Macchia, Marco; Di Modugno, Enza; Balsamo, Aldo Farmaco, 2004 , vol. 59, # 9 p. 691 - 696

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Citation Number: 3

Abstract

Selected 7β-(benzo [a] dihydrocarbazolyloxyacetyl)-substituted cephalosporins (1a–e) were synthesised and tested for their antimicrobial activity against Gram-positive and Gram- negative clinical pathogens. All compounds synthesised (1a–e) showed an in vitro antimicrobial activity similar to that of ceftriaxone and cefpirome against the Gram-positive bacteria, and superior to that of penicillin and cefaclor against pen-R Staphylococcus ...