4-(Aminoalkyl)-7-hydroxy-2 (3H)-indolones, a novel class of potent presynaptic dopamine receptor agonists

WF Huffman, RF Hall, JA Grant, JW Wilson…

Index: Huffman; Hall; Grant; Wilson; Hieble; Hahn Journal of Medicinal Chemistry, 1983 , vol. 26, # 7 p. 933 - 935

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Citation Number: 23

Abstract

1345, Abstract 6281. SK&F 85174 was originally prepared in our laboratories by Dr. Martin Brenner.(3) The cardiovascular properties of di-n-propyldopamine have been studied in spontaneously hypertensive rats by Cavero and co-workers (see ref 6). Similar studies carried out independently in our laboratories by R. Hahn and J. Stefankiewicz are in agreement with the results of Cavero et al.(4) See, for instance, Kobinger, W. In" ...

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Syntheses and in vitro evaluation of 4-(2-aminoethyl)-2 (3H)-indolones and related compounds as peripheral prejunctional dopamine receptor agonists

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