Tetrahedron

3-Indolylphosphines as ligand for palladium in Suzuki–Miyaura coupling reaction of chloroarenes: substituent effects

D Saha, R Ghosh, A Sarkar

Index: Saha, Debajyoti; Ghosh, Raju; Sarkar, Amitabha Tetrahedron, 2013 , vol. 69, # 19 p. 3951 - 3960

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Citation Number: 9

Abstract

The ligand 1, 3-bis (diphenylphosphino)-1H-indole, L1 with palladium promotes Suzuki– Miyaura coupling reaction of chloroarenes and benzyl chlorides with arylboronic acids. Structural modification of L1 established that the phosphine group at C-3 position of indole was crucial to catalysis and its efficacy depended on the nature of the N-substituent. 31P chemical shift values of the substituted indolylphosphines appear to show a correlation ...

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