The Journal of organic chemistry

Glucopyranoside recognition by polypyridine-macrocyclic receptors possessing a wide cavity with a flexible linkage

M Inouye, J Chiba, H Nakazumi

Index: Inouye, Masahiko; Chiba, Junya; Nakazumi, Hiroyuki Journal of Organic Chemistry, 1999 , vol. 64, # 22 p. 8170 - 8176

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Citation Number: 43

Abstract

New polypyridine-macrocyclic receptors for glucopyranosides were designed and synthesized. The artificial receptors possess a terpyridine skeleton as a hydrogen-bonding site and a flexible polyoxyethylene chain as a bridge for the macrocyclic structure, in which the cavity of the receptors is large enough to incorporate pyranosides. The receptors showed high affinities for n-octyl β-(d)-glucopyranoside, and selective binding of the ...