An oxidative cross-dehydrogenative-coupling reaction in water using molecular oxygen as the oxidant: vanadium catalyzed indolation of tetrahydroisoquinolines
K Alagiri, GSR Kumara, KR Prabhu
Index: Alagiri, Kaliyamoorthy; Kumara, Guralamatta Siddappa Ravi; Prabhu, Kandikere Ramaiah Chemical Communications, 2011 , vol. 47, # 42 p. 11787 - 11789
Full Text: HTML
Citation Number: 47
Abstract
An aerobic oxidative cross-dehydrogenative coupling reaction between sp3 C–H and sp2 C– H bonds is developed by employing a vanadium catalyst (10 mol%) in an aqueous medium using molecular oxygen as the oxidant. This environmentally benign strategy exhibits larger substrate scope and shows high regioselectivity.
Related Articles:
[Tsang, Althea S.-K.; Ingram, Katrin; Keiser, Jennifer; Hibbert, D. Brynn; Todd, Matthew H. Organic and Biomolecular Chemistry, 2013 , vol. 11, # 30 p. 4921 - 4924]
An Aromatic Amination Approach towards Ancistrocladinium A/B
[Buckley, Benjamin R.; Christie, Steven D. R.; Elsegood, Mark R. J.; Gillings, Claire M.; Page, Philip C. Bulman; Pardoe, William J. M. Synlett, 2010 , # 6 p. 939 - 943]
Facile synthesis of vicinal diamines via oxidation of N-phenyltetrahydroisoquinolines with DDQ
[Tsang, Althea S.-K.; Todd, Matthew H. Tetrahedron Letters, 2009 , vol. 50, # 11 p. 1199 - 1202]
[Hou, Zhe; Yang, Rui; Zhang, Cen; Zhu, Li-Fei; Miao, Fang; Yang, Xin-Juan; Zhou, Le Molecules, 2013 , vol. 18, # 9 p. 10413 - 10424]
[Hou, Zhe; Yang, Rui; Zhang, Cen; Zhu, Li-Fei; Miao, Fang; Yang, Xin-Juan; Zhou, Le Molecules, 2013 , vol. 18, # 9 p. 10413 - 10424]