Bioorganic & medicinal chemistry

Synthesis of 7-chloro-5-trifluoromethyl/7-fluoro/7-trifluoromethyl-4H-1, 4-benzothiazines as antimicrobial agents

BS Rathore, M Kumar

Index: Rathore, Bhawani Singh; Kumar Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 16 p. 5678 - 5682

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Citation Number: 72

Abstract

7-Chloro-5-trifluoromethyl/7-fluoro/7-trifluoromethyl-4H-1, 4-benzothiazines have been synthesized by 2-amino-5-fluoro/5-trifluoromethyl/5-chloro-3-trifluoromethyl benzenethiols condensed with β-diketone/β-ketoesters in the presence of DMSO involving oxidative