Indium Tribromide Catalyzed Cross??Claisen Condensation between Carboxylic Acids and Ketene Silyl Acetals Using Alkoxyhydrosilanes

Y Nishimoto, A Okita, M Yasuda…

Index: Nishimoto, Yoshihiro; Okita, Aya; Yasuda, Makoto; Baba, Akio Angewandte Chemie - International Edition, 2011 , vol. 50, # 37 p. 8623 - 8625

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Citation Number: 21

Abstract

Carbon acylations play an important role in the construction of carbon frameworks having a carbonyl group. Among them, the Claisen condensation is one of the most useful methods, as it furnishes various β-ketoesters.[1] A classical example is the homocondensation of esters promoted by a strong base.[2] Recent successful developments in the cross- condensation between metal enolates and active acylating reagents, such as acid ...