Regiochemical diversity in allylic alkylations via molybdenum catalysts

BM Trost, M Lautens

Index: Trost, Barry M.; Lautens, Mark Tetrahedron, 1987 , vol. 43, # 21 p. 4817 - 4840

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Citation Number: 70

Abstract

The use of molybdenum as a template to control regioselectivity in allylic alkylations is explored. The feasibility of performing allylic alkylations with preformed π-allylmolybdenum complexes is established. As in palladium reactions, addition of excess phosphine has a profound effect on the rate of these reactions. A catalytic reaction based upon molybdenum hexacarbonyl is developed. Using malonate anion, excellent regioselectivity for attack at ...