New synthesis of trifluorinated amines from 1-bromopropargylic amines in superacid
…, H Carreyre, JP Gesson, B Renoux, MP Jouannetaud
Index: Cantet, Anne-Celine; Carreyre, Helene; Gesson, Jean-Pierre; Renoux, Brigitte; Jouannetaud, Marie-Paule Tetrahedron Letters, 2006 , vol. 47, # 31 p. 5547 - 5551
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Citation Number: 3
Abstract
Considerable attention has been given to fluorinated organic compounds due to their potential use in medicinal and agricultural chemistry. 1 Interest in these fluorinated substances is continuously increasing because introduction of one or more fluorine atoms 2 may significantly modify the chemical, physical, and biological properties of such substances. These modifications are associated with increased stability and lipophilicity, while the steric distortion, compared to the parent ...