MIRC reactions. 3. Use of doubly activated substrates
RD Little, R Verhe, WT Monte, S Nugent…
Index: Little, R. Daniel; Verhe, Roland; Monte, William T.; Nugent, Sean; Dawson, James R. Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 362 - 364
Full Text: HTML
Citation Number: 29
Abstract
We recently reported the formation of three-, five-, six-, and seven-membered-ring esters bearing P-heteroatom substituents, through the utilization of what we have termed a MIRC (Michael Initiated Ring Closure) reacti0n. l Herein, we provide (1) a rationale for the use of geminate doubly activated w-halo a,@-unsaturated esters rather than monoactivated systems as substrates for the MIRC reaction and (2) evidence which demonstrates that the ...
Related Articles:
[Davis, Charles R.; Swenson, Dale C.; Burton, Donald J. Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6843 - 6850]
[Nugent, Sean T.; Baizer, Manuel M.; Little, R. Daniel Tetrahedron Letters, 1982 , vol. 23, # 13 p. 1339 - 1342]
[Davis, Charles R.; Swenson, Dale C.; Burton, Donald J. Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6843 - 6850]
Perkin-Markovnikov type reaction initiated with electrogenerated superoxide ion.
[Ojima; Osa Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3187 - 3194]