A strategy for the total synthesis of jatrophone: synthesis of normethyljatrophone

…, MA Guaciaro, SR Schow, PM Wovkulich…

Index: Smith, Amos B.; Guaciaro, Michael A.; Schow, Steven R.; Wovkulich, Peter M.; Toder, Bruce H.; Hall, Tse Wai Journal of the American Chemical Society, 1981 , vol. 103, # 1 p. 219 - 222

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Citation Number: 77

Abstract

(5)(6)(a): R= CH,(b): R= H are the spiro-3 (2H)-furanone, the macrocyclic ring, and the cross- conjugated trienone functionalities. Recently, we have made considerable progress toward the development of a viable synthetic strategy for the elaboration of jatrophone. We now wish to announce completion of the synthesis of normethyljatrophone (2), the alicyclic backbone of this novel diterpene. Our strategy for both jatrophone and the normethyl ...