Tetrahedron Letters

Total synthesis of (+) pseudophrynaminol

MO Mitchell, PW Le Quesne

Index: Mitchell, Miguel O.; Le Quesne, Philip W. Tetrahedron Letters, 1990 , vol. 31, # 19 p. 2681 - 2684

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Citation Number: 18

Abstract

1 HNMR of 5(CDCl 3 , TMS reference, 300 MHz): δ a l.24 (t) and δ b l.33 (O (two rotamers, 3H total. J a = J b = 7.1-7.2 Hz), 1.53 (s, 3H), 1.71 (s, 3H), 2.13–2.17 (m, 2H), 2.35–2.39 (m, 2H), 3.02–3.06 (m, 1H), 3.55–3.75 (two rotamers, apparent quartets, J =7.1–7.2 Hz for both, 2H total), 5.10 (s, 1H), 5.07–5.18 (m, 1H and D 2 O exchangeable proton, 2H total), 6.60 (d, 1H, J =7.7 Hz) 6.73–6.76 (m, 1H), 7.05 (d, 1H, J = 7.5 Hz), 7.09 (d, 1H, J = 1.4 Hz). IR of 5 (60 ...