Application of the BHQ benzannulation reaction to the synthesis of benzo-fused coumarins
JA Bull, C Luján, MG Hutchings, P Quayle
Index: Bull, James A.; Lujan, Cristina; Hutchings, Michael G.; Quayle, Peter Tetrahedron Letters, 2009 , vol. 50, # 26 p. 3617 - 3620
Full Text: HTML
Citation Number: 7
Abstract
A new approach to the synthesis of the 6H-benzo [d] naphtha [1, 2-b] pyran-6-one ring system present in the gilvocarcin family of antibiotics is described. The key feature of this approach is the application of a new benzannulation strategy (the 'BHQ Reaction') whereby readily available ortho-allylaryl trichloroacetates are transformed into naphthalene derivatives via a cascade of reactions involving an initial ATRC reaction followed by the ...
Related Articles:
Synthesis and antifungal activity of coumarins and angular furanocoumarins
[Sardari, Soroush; Mori, Yoki; Horita, Kiyoshi; Micetich, Ronald G.; Nishibe, Sansei; Daneshtalab, Mohsen Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 9 p. 1933 - 1940]