Advanced Synthesis & Catalysis

Synthesis of α??Diazo Carbonyl Compounds with the Shelf??Stable Diazo Transfer Reagent Nonafluorobutanesulfonyl Azide

JL Chiara, JR Suárez

Index: Chiara, Jose Luis; Suarez, Jose Ramon Advanced Synthesis and Catalysis, 2011 , vol. 353, # 4 p. 575 - 579

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Citation Number: 17

Abstract

Abstract Nonafluorobutanesulfonyl azide is a shelf-stable, cost-effective and general diazo transfer reagent for the efficient synthesis of α-diazo carbonyl compounds in excellent yields and in very short reaction times, under mild conditions. The diazo products can be readily isolated in pure form after a simple aqueous extractive work-up that avoids chromatographic purification in most cases. Because of its high efficiency and wide substrate scope, shelf- ...