Tetrahedron letters

Enantioselective total synthesis of cineromycin B

T Takahashi, H Watanabe, T Kitahara

Index: Takahashi, Tatsuhisa; Watanabe, Hidenori; Kitahara, Takeshi Tetrahedron Letters, 2003 , vol. 44, # 51 p. 9219 - 9222

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Citation Number: 17

Abstract

The enantioselective total synthesis of cineromycin B, a 14-membered unsaturated macrolide with two doubly allylic alcohols, was completed using a Julia coupling, an oxidative [2, 3]-sigmatropic rearrangement of selenide, and a Yamaguchi macrolactonization as key reactions.