Microbiological hydroxylation. Part 23. Bicyclic substrates for steroid-hydroxylating fungi

AS Bailey, ML Gilpin, ERH Jones

Index: Bailey; Gilpin; Jones Journal of the Chemical Society. Perkin transactions 1, 1977 , # 3 p. 265 - 270

Full Text: HTML

Citation Number: 11

Abstract

Bicyclic oxygen-containing substrates have been hydroxylated by Calonectria decora and by Rhizopus nigricans. Poor yields of mono- and di-oxygenated compounds were obtained. Initial attack appears to occur at carbon atoms remote from the original oxygen function. ... IN the preceding paper we described the preparation of a set of bicyclic ketones and alcohols containing 15- 16 carbon atoms. The microbiological hydroxylations of some of these compounds have now ...