Alkylamination of pteridines by primary alkylamines??potassium permanganate

H Sladowska, A Van Veldhuizen…

Index: Sladowska, H.; van Veldhuizen, A.; van der Plas, H. C. Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 843 - 847

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Citation Number: 5

Abstract

Abstract Reaction of 7-phenyl, 7-p-methoxyphenyl, 7-t-butyl-and 6, 7-diphenylpteridine with ethylamine and t-butylamine in the presence of potassium permanganate leads to the introduction of the ethylamino or t-butylamino group at C-4 in the above-mentioned pteridines. In the reaction of ethylamine/potassium permanganate besides the 4- (ethylamino) pteridine derivatives 2-amino-3-formytpyrazines are obtained as side- ...