Synthesis and antibiotic activity of a small molecules library of 1, 2, 3-triazole derivatives
M Aufort, J Herscovici, P Bouhours, N Moreau…
Index: Aufort, Marie; Herscovici, Jean; Bouhours, Pascale; Moreau, Nicole; Girard, Christian Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 3 p. 1195 - 1198
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Citation Number: 73
Abstract
A small library of simple 1, 4-disubstituted 1, 2, 3-triazoles was prepared using a known one- pot procedure starting from organic halides and terminal alkynes. The compounds were then tested for their antibacterial activity against normal and resistant species of Staphylococcus aureus.
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