Tetrahedron

A family of stilbene-ethers as photolabile protecting groups for primary alcohols offers controlled deprotection based on choice of wavelength

JH Ho, YW Lee, YZ Chen, PS Chen, WQ Liu, YS Ding

Index: Ho, Jinn-Hsuan; Lee, Ya-Wen; Chen, Ying-Zhe; Chen, Pin-Sian; Liu, Wei-Qi; Ding, Yi-Shun Tetrahedron, 2013 , vol. 69, # 35 p. 7325 - 7332

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Citation Number: 2

Abstract

Abstract A novel stilbene-ether type of photolabile protecting group (PPG) for hydroxyl group has been developed. It contains a stable aryl ether group in the protected form and can be deprotected by acid-catalyzed photorearrangement under 300-nm irradiation. The selective deprotection has also been achieved by irradiation of the mixture of 4-alkoxystilbene and 2- (4-alkoxystyryl) furan at 365 nm.

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