Efficient copper-catalyzed chemo selective conjugate addition of aliphatic amines to α, β-unsaturated compounds in water

LW Xu, JW Li, CG Xia, SL Zhou, XX Hu

Index: Xu, Li-Wen; Li, Jing-Wei; Xia, Chun-Gu; Zhou, Shao-Lin; Hu, Xiao-Xue Synlett, 2003 , # 15 p. 2425 - 2427

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Citation Number: 61

Abstract

The recent interest in aqueous medium metal-mediated carbon-carbon and carbon-heteroatom and formations led to the contributors for such reactions. [15] Although various kinds of Lewis acids and bases have been applied in aza-Michael reaction, these Lewis acids and bases generally must be used under strictly anhydrous conditions, because the presence of even a small amount of water stops the reactions. [16] On the other hand, in the course of investigations on ...