Catalytical promiscuity of α-amylase: synthesis of 3-substituted 2H-chromene derivatives via biocatalytic domino oxa-Michael/aldol condensations
LH Zhou, N Wang, W Zhang, ZB Xie, XQ Yu
Index: Zhou, Long-Hua; Wang, Na; Zhang, Wei; Xie, Zong-Bo; Yu, Xiao-Qi Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 91, p. 37 - 43
Full Text: HTML
Citation Number: 11
Abstract
Abstract An facile and green one-pot route has been developed for the synthesis of chromenes using salicylaldehyde and α, β-unsaturated ketones. α-Amylase from Bacillus subtilis shows excellent catalytic activity and exerts good adaptability to different substrates in the reaction. This promiscuous enzyme-catalyzed domino reaction not only extends the application of α-amylase from B. subtilis for new chemical transformations, but also ...
Related Articles:
[Shin, Soon Young; Jung, Hyeryoung; Ahn, Seunghyun; Hwang, Doseok; Yoon, Hyuk; Hyun, Jiye; Yong, Yeonjoong; Cho, Hi Jae; Koh, Dongsoo; Lee, Young Han; Lim, Yoongho Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 6 p. 1809 - 1820]
[La Pietra, Valeria; Marinelli, Luciana; Cosconati, Sandro; Di Leva, Francesco Saverio; Nuti, Elisa; Santamaria, Salvatore; Pugliesi, Isabella; Morelli, Matteo; Casalini, Francesca; Rossello, Armando; La Motta, Concettina; Taliani, Sabrina; Visse, Robert; Nagase, Hideaki; Da Settimo, Federico; Novellino, Ettore European Journal of Medicinal Chemistry, 2012 , vol. 47, # 1 p. 143 - 152]
[Foroumadi, Alireza; Emami, Saeed; Sorkhi, Maedeh; Nakhjiri, Maryam; Nazarian, Zohreh; Heydari, Samaneh; Ardestani, Sussan K.; Poorrajab, Fatemeh; Shafiee, Abbas Chemical Biology and Drug Design, 2010 , vol. 75, # 6 p. 590 - 596]