Tetrahedron Letters

A novel synthesis of 4-cycloheptenones

EN Marvell, D Titterington

Index: Marvell, Elliot N.; Titterington, Donald Tetrahedron Letters, 1980 , vol. 21, p. 2123 - 2124

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Citation Number: 19

Abstract

A broad variety of sesquiterpenes, mono and bicyclic, either incorporate or are readily accessible from compounds having a 4-cycloheptenone moiety.' It appeared that the synthesis of Demole and Enggist,2 studied in detail by Rhoads, would be very useful if generalized. The major problem rests in the preparationof Z-methylene-5-vinyltetrahydrofurans. We describe here a novel solution to the problem, its advantages and some limitations. The approach is dependent on the ...

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