An original chemoenzymatic route for the synthesis of β-D-galactofuranosides using an α-L-arabinofuranosidase

…, R Plantier-Royon, N Aubry, MJ O'Donohue

Index: Remond, Caroline; Plantier-Royon, Richard; Aubry, Nathalie; O'Donohue, Michael J. Carbohydrate Research, 2005 , vol. 340, # 4 p. 637 - 644

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Citation Number: 35

Abstract

Galactofuranose is a widespread component of cell wall polysaccharides in bacteria, protozoa and fungi, but is totally absent in mammals. Importantly, galactofuranose is a key constituent of major cell envelope polysaccharides in pathogenic mycobacteria. In this respect, galactofuranose-based glycoconjugates are interesting target molecules for drug design. O-Glycosidases and notably β-d-galactofuranosidases could be useful tools for ...