Metabolism of N-alkyldiamines and N-alkylnortropinones by transformed root cultures of Nicotiana and Brugmansia

HD Boswell, B Dräger, J Eagles, C McClintock, A Parr…

Index: Boswell, Henry D.; Draeger, Birgit; Eagles, John; McClintock, Carol; Parr, Adrian; Portsteffen, Andreas; Robins, David J.; Robins, Richard J.; Walton, Nicholas J.; Wong, Chi Phytochemistry, 1999 , vol. 52, # 5 p. 855 - 869

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Citation Number: 17

Abstract

A range of analogues of N-methylputrescine and tropinone were fed to transformed root cultures of Nicotiana rustica and/or a Brugmansia candida× aurea hybrid. These cultures were made by the transformation of the relevant plant species with Agrobacterium rhizogenes. A number of the metabolites, notably those showing a relatively modest alteration in the N-alkyl substituent, were metabolized in vivo to form homologues of the ...