Synthesis and application of phosphinoferrocenylaminophosphine ligands for asymmetric catalysis

…, EB Mackenzie, SD Debenham, SE Large…

Index: Boaz, Neil W.; Mackenzie, Elaine B.; Debenham, Sheryl D.; Large, Shannon E.; Ponasik Jr., James A. Journal of Organic Chemistry, 2005 , vol. 70, # 5 p. 1872 - 1880

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Citation Number: 80

Abstract

A new class of bidentate ligands utilizing a phosphine-aminophosphine structure has been prepared on a ferrocenylethyl backbone in a straightforward and scalable fashion from acetylferrocene. The unique property of the α-ferrocenyl carbonium ion that allows the replacement of a variety of “leaving groups” with retention of configuration greatly facilitates the synthesis, and a number of ligands have been prepared by varying the nitrogen and ...

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