Low temperature asymmetric epoxidation of unfunctionalized olefins catalyzed by (salen) Mn (III) complexes

M Palucki, GJ McCormick, EN Jacobsen

Index: Palucki, Michael; McCormick, Gregory J.; Jacobsen, Eric N. Tetrahedron Letters, 1995 , vol. 36, # 31 p. 5457 - 5460

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Citation Number: 247

Abstract

The enantioselective epoxidation of olefins catalyzed by (salen) Mn (III) complexes can be effected under anhydrous conditions with a variety of primary oxidant systems. The combination of m-CPBA and NMO is particularly reactive, allowing for epoxidation reactions to be carried out at− 78° C. Under these low temperature conditions, a variety of unfunctionalized olefins undergo epoxidation with a significant increase in ...